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Vascularized Joint Transplantation

Vascularized joint
Composite tissue transplant - skin, tendon, nerve, bone, cartilage
Sensate
No - skin paddle can be made sensate
Blood supply
First dorsal metatarsal artery via the dorsalis pedis artery, or plantar digital artery via the lateral plantar artery
Artery
Can be less than 1 millimeter if taken distally, a  progressively larger caliber when dissected more proximally
Vein(s)
The dorsal subcutaneous venous system usually used, or secondarily  the venae of the first dorsal metatarsal artery  and dorsalis pedis artery can be used
Pedicle length
Can be dissected up to the anterior tibial artery in some cases for great length

 

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LOWER EXTREMITY FLAPS
Anterolateral Thigh flap
Great Toe Transplantation
Second Toe Transplantation
Fibula Flap with Skin Paddle
Fibula Flap
Dorsalis Pedis Flap
Extensor Brevis muscle flap
Gracilis Muscle Flap
Vascularized Joint Transplant

 

Small joint arthroplasty of the metatarsophalangeal and proximal interphalangeal joints can be challenging and is often limited to the low demand patient population.  The vascularized joint can in selected cases of trauma or congenital absence offer joint replacement that is permanent and functional.  Additionally, because an open epiphysis continues to develop after transplantation, reconstruction in children has the potential for growth.  Stiffness can be problematic, but less so in the younger patient population.  Both the pip joint of the second toe and the mp joint of the second toe have been used for small joint reconstruction.

 

Preoperative Assessment

Any traumatic injury or congenital absence requires a thorough preoperative evaluation by the microsurgeon. The hand is thoroughly assessed to determine the anatomy of the loss and the potential requirements for reconstruction. If a vascularized joint transplant is felt to be the reconstruction of choice, the surgeon must evaluate the lower extremity completely. This includes a history of previous injury or surgery, and a complete skeletal, vascular and sensorimotor examination. Particular attention should be paid to the pedal pulses. If arterial inflow is thought to be questionable whether by history or physical examination, then an angiographic study of the lower extremity is performed. We however do not routinely perform angiography of the lower extremity because we have found the vessel spasm of the foot to be particularly problematic in angiography, and this often leads to results that are of no value in determining toe vascular anatomy. In healthy individuals with no clear indication for angioraphy, the study does not help the surgeon either plan or execute the surgical procedure.

Anatomy

The joints of the second toe are used.  Either the metatarsophalangeal joint or the proximal interphalangleal joint.  The mp joints of the foot are primarily extension joints with significantly more range of motion in extension.  The opposite is true for the pip joint.  When the mp joint is used for reconstruction therefore, it is typically placed with its extensor surface volarly and the flexor surface dorsally, thus maximizing finger flexion at the joint.

The vascular supply to the second toe is via the first dorsal metatarsal artery, a continuation of the dorsalis pedis artery. The first dorsal metatarsal can remain entirely dorsal, or in greater than 50% of cases, dives deep between the first and second metatarsal, to provide a plantar dominant inflow to the second toe. In the first web space, the termination of the plantar or dorsal dominant system can always be found sending branches to the second  toe and great toe.

Plantar to these branches are the digital nerves to the great and second toe and the transverse metatarsal ligament. The second toe has both long and short extensors, with the long tendon used to power the toe in the hand. The flap is typically disarticulated at the metatarsophalangeal joint, but it can also be taken distal to this level. More distally, great caution must be taken not to injure the small digital vessel supplying arterial inflow.

 

Operative Procedure

The second toe is dissected in the manner describe in the second toe transplantation section. 

When the second toe is isolated, before or after the arterial inflow and draining vein are divided, the toe is trimmed of tissue that is not required.  If the pip joint is being used, as in the figure below, osteotomies are made on the middle and proximal phalanx, leaving behind the vascular supply and drainage, as well as any tendons that will be used.  A small cuff of soft tissue is left subcutaneously while a skin paddle remains for monitoring.

If the mp joint is to be used, the distal metatarsal is harvested with the toe.  The distal osteotomy is performed on the proximal phalanx after distal soft tissue is removed.

Left behind are a skin paddly and inflow and outflow vessels.  Nerve supply and tendon supply is optional depending on the reconstruction.

Post-Operative Care

The foot is kept elevated for the first week and then introduced to a progressive dangling regimen.  An ace wrap can provide gentle compression during dangling.  Weight bearing is not begun until the donor site is well healed, often not until four to six weeks.  During this time crutch use can be difficult because use of the reconstructed hand is limited.  In bilateral toe transplants crutches are not used.  In these cases special shoes that keep the feet in exaggerated dorsiflexion can be used to limit plantar weight and transfer weight to the heels. 

Significant wound complications are rare in the healthy patient.  If a vascular complication in the transplanted toe requires systemic patient heparinization, then hemorrhage into the second metatarsal space can cause ecchymosis, flap necrosis and delayed healing.  This is treated according to the severity of any wound development.  Rehabilitation with dangling and subsequent ambulation are delayed.